Over the past decade, efforts have been made to promote conservation agriculture as an ecologically sound alternative to tillage-based agriculture in the Lao People’s Democratic Republic (PDR). This paper assesses some of the outcomes of a five-year research project aimed at developing sustainable no-till cropping and pasture systems and promoting their adoption by smallholders in Xieng Khouang province. Based on extensive household surveys in 20 villages, it highlights key environmental and socioeconomic factors influencing the adoption and diffusion of conservation agriculture. Finally, it provides policy recommendations to facilitate agricultural innovation and provide greater incentives for farmers to shift towards more sustainable farming practices.